Medication: Zestoretic (Combination)
Written by: jchodirker | Posted: Apr 27 2009
How Zestoretic Reduces Blood Pressure
Zestoretic is a combination of Lisinopril and Hydrochlorothiazide (HCTZ).
Lisinopril is an Angiotestin Converting Enzyme Inhibitor or more commonly known as ACE Inhibitors. Angiotensin II is a chemical that causes the muscles surrounding the blood vessels to contract (tighten). This in turn narrows the blood vessels. This narrowing increases the pressure within the blood vessels and can cause high blood pressure (hypertension). Lisinopril slows (inhibits) the activity of the enzyme, which decreases the production of angiotensin II. As a result, the blood vessels enlarge or dilate, and the blood pressure is reduced.
HCTZ is a thiazide diuretic (water pill) decreases the amount of fluid in your body by increasing the amount of salt and water you lose in your urine.
The combination of these two drugs forms Zestoretic which is used to treat blood pressure.
Other combination drugs include Avalide, Dyazide, and Lotrel.
Although these medications are beneficial, many times they are not enough to control your blood pressure.
Click here for additional information including side effects.
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